Significance of Cd
Cadmium (Cd) is shown to accumulate intracellular reactive oxygen species (ROS), leading to the activation of the NLRP3 inflammasome in human umbilical vein endothelial cells (HUVECs). This activation plays a significant role in promoting pyroptosis, which is a form of programmed cell death associated with inflammation. The findings highlight the detrimental effects of cadmium exposure on cellular health and its potential implications for cardiovascular diseases.
Synonyms: Disc, Optical disc
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The concept of Cd in scientific sources
Cd, or Cadmium, is linked to the accumulation of intracellular reactive oxygen species (ROS), leading to the activation of the NLRP3 inflammasome in human umbilical vein endothelial cells (HUVECs) and the promotion of pyroptosis.
From: The Malaysian Journal of Medical Sciences
(1) Cadmium, a metal whose presence in blood has been associated with total serum PSA levels, indicating a potential relationship.[1] (2) This is a condition known as Crohn’s disease, and it increases the risk of colitis-associated CRC.[2] (3) Cadmium has also been demonstrated to accumulate intracellular ROS, which induces NLRP3 inflammasome activation in HUVECs, and promotes pyroptosis.[3]