Significance of Caspases
Caspases are a crucial family of cysteine protease enzymes that play essential roles in programmed cell death, known as apoptosis. They function as both initiators and executioners in the apoptotic process, with specific types like procaspase 7 highlighted in related studies. Research indicates an up-regulation of these proteases in certain cell lines, suggesting their significant involvement in the apoptotic pathways. In addition to apoptosis, caspases also participate in inflammation, underscoring their importance in cellular processes.
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of Caspases in scientific sources
Caspases are a family of cysteine proteases essential for initiating and executing apoptosis, effectively regulating the cell death process. Their role is crucial in managing cellular responses during apoptosis.
From: The Malaysian Journal of Medical Sciences
(1) These are enzymes involved in programmed cell death, and the text mentions their role in various conditions.[1] (2) An increase in initiator and executioner types of these was observed, which suggests the up-regulation of the apoptotic pathway in HCT116 and HT-29 cells.[2]