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Significance of Brine shrimp lethality assay

The Brine shrimp lethality assay is a bioassay used to evaluate the cytotoxicity of various substances by measuring their impact on the mortality rates of brine shrimp, specifically Artemia salina. This experimental method serves as a preliminary screening tool for determining toxicity, correlating findings with potential cytotoxic effects in human tumors. By observing the effects of different concentrations of test extracts on brine shrimp, researchers can gain insights into the potential toxicity of chemical compounds.

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The concept of Brine shrimp lethality assay in scientific sources

Science Books

The Brine shrimp lethality assay is a bioassay technique that evaluates the toxicity of substances by measuring the mortality rate in brine shrimp larvae (Artemia salina) exposed to various concentrations of test extracts.

Significance in Scientific journals, articles, etc.:

From: World Journal of Pharmaceutical Research

(1) A preliminary method used to assess the cytotoxic activity of extracts by observing their effects on brine shrimp.[1] (2) A bioassay used for primary screening of toxicity towards brine shrimp, correlated with cytotoxicity in human tumors.[2] (3) A simple bioassay that uses brine shrimp (Artemia salina) to evaluate the toxicity of a substance or extract.[3] (4) A biological test used to evaluate the toxicity of substances by observing their effect on brine shrimp larvae.[4] (5) A bioassay used to assess the cytotoxicity of substances by measuring their effects on the mortality of brine shrimp, providing an indication of potential toxicity in living organisms.[5]

From: Journal of Ayurveda and Integrative Medicine

(1) A method used for screening the toxicity of compounds by observing their effects on brine shrimp.[6] (2) An experimental method used to assess the toxicity of substances by measuring the mortality rate of brine shrimp when exposed to those substances.[7]

From: AYU (Journal of Research in Ayurveda)

(1) A method used to determine the toxicity of substances by assessing the mortality rate of brine shrimp (Artemia salina) when exposed to different concentrations of a test extract.[8]

This section includes scientific research in the field of healthcare, often involving traditional medicine systems such as Ayurveda, Unani, Siddha and Holistic health. It includes papers from scientific journals classified as either original, clinical or experimental research, review articles or case reports.