Significance of Blast cells
Blast cells are immature blood cells associated with acute lymphoblastic leukaemia, which are specifically targeted by the enzyme L-asparaginase to decrease their levels in the body. Additionally, these cells include immature lymphocytes that are rapidly dividing and differentiating as part of an active immune response, highlighting their significance in both pathological conditions and the body's defense mechanisms.
Synonyms: Immature cells, Progenitor cells
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The concept of Blast cells in scientific sources
Blast cells are immature lymphocytes involved in immune responses, and their proliferation is a hallmark of acute lymphoblastic leukaemia, where they are targeted by treatments like L-asparaginase to lower their presence in the body.
From: The Malaysian Journal of Medical Sciences
(1) These are immature blood cells, and with nuclear extrusions in the form of micronuclei are associated with MYC amplification in acute myeloid leukemia, and are an indicator of leukemia.[1] (2) These are immature blood cells that are characteristic of acute lymphoblastic leukaemia, and they are targeted by L-asparaginase to reduce their numbers in the body.[2]