Significance of ADME
ADME stands for Absorption, Distribution, Metabolism, and Excretion, which are critical pharmacokinetic properties of compounds. These properties play a significant role in determining the effectiveness of drugs by influencing how they are absorbed in the body, distributed to various tissues, metabolized into different forms, and ultimately excreted. Understanding ADME is essential in the field of drug development and pharmacology, as it helps in evaluating the therapeutic potential and safety of pharmaceutical compounds.
Synonyms: Absorption, Distribution, Metabolism, Excretion
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The concept of ADME in scientific sources
ADME stands for Absorption, Distribution, Metabolism, and Excretion, which are crucial pharmacokinetic properties that influence the efficacy and behavior of pharmaceutical compounds in the body.
From: Journal of Ayurveda and Holistic Medicine
(1) An acronym for Absorption, Distribution, Metabolism, and Excretion, referring to the pharmacokinetic properties of compounds that determine their effectiveness as drugs.[1]
From: World Journal of Pharmaceutical Research
(1) An acronym for Absorption, Distribution, Metabolism, and Excretion, key properties in pharmacokinetics determining drug behavior in the body.[2]