Significance of Acute toxicity test
The acute toxicity test is a procedure designed to evaluate the harmful effects of a substance after a single dose administration, focusing on animal survival and behavioral changes. This test assesses the safety of various extracts, including those from plants like Peuraria phaseoloides and Ficus polita, or substances like methanolic extracts by observing any toxic effects, lethal doses (LD50), and overall safety in laboratory animals. Conducted across different studies, it helps determine the safety profiles of numerous substances.
Synonyms: Short-term toxicity test, Toxicity testing, Hazard assessment
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of Acute toxicity test in scientific sources
The Acute toxicity test evaluates the lethal dose (LD50) of substances like LIHE and assesses the safety of GMME in male Wistar rats, focusing on potential toxic effects at high doses.
From: The Malaysian Journal of Medical Sciences
(1) An assessment to determine the toxicity level of a substance, in this case using albino mice and monitoring for adverse effects post-exposure.[1] (2) A method used to assess the toxic effects of substances through their administration in various doses to measure potential harm.[2]