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Significance of Acute toxicity study

An acute toxicity study is a crucial evaluation of the harmful effects of a drug formulation or substance following a single dose or short-term exposure. It aims to assess the potential harmful effects, establishing safety profiles by determining median lethal doses (LD50) and monitoring for adverse effects in living organisms. This type of research involves administering high or specified doses to subjects, ensuring safety by confirming the absence of adverse effects or mortality within set parameters.

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The concept of Acute toxicity study in scientific sources

Science Books

The Acute toxicity study is a preliminary evaluation of the toxic effects of substances on organisms, employing metrics like LD50, and facilitating safety assessments of various formulations, including Vasaguduchyadi Kwatha and Tamra Bhasma, over short periods.

Significance in Scientific journals, articles, etc.:

From: The Malaysian Journal of Medical Sciences

(1) An evaluation conducted to assess the safety and potential harmful effects of a substance at high doses over a short period.[1]

This section includes scientific research in the field of healthcare, often involving traditional medicine systems such as Ayurveda, Unani, Siddha and Holistic health. It includes papers from scientific journals classified as either original, clinical or experimental research, review articles or case reports.