Significance of Absorption Enhancer
Absorption enhancers are agents designed to improve the uptake and permeability of drugs across biological membranes, thereby enhancing drug delivery and bioavailability. They function by facilitating the absorption of therapeutic substances through various routes, including gastrointestinal and nasal pathways. By altering the characteristics of membranes or drug formulations, absorption enhancers make it easier for larger or poorly soluble drug molecules to penetrate these barriers. Their application is particularly significant in developing more effective drug delivery systems.
Synonyms: Bioavailability booster, Penetration enhancer, Permeation enhancer, Bioavailability enhancer
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of Absorption Enhancer in scientific sources
Absorption Enhancers are substances that enhance the absorption of larger drug molecules via the nasal route, improving drug uptake through the nasal mucosa and potentially increasing efficacy when used with Nasya treatments.
From: World Journal of Pharmaceutical Research
(1) Agents that improve the uptake of drugs in the gastrointestinal tract, enhancing the efficiency of drug delivery systems.[1] (2) Substances that increase the permeability of the mucosal tissues to enhance the absorption of drugs through the buccal or sublingual route.[2] (3) Substances that improve the uptake of drugs by increasing their permeability across biological barriers.[3] (4) Absorption enhancers are agents that increase the permeability of biological membranes, aiding in the absorption of therapeutic substances.[4] (5) Compounds that improve the absorption of drug molecules in the body, thereby increasing their bioavailability.[5]
From: International Ayurvedic Medical Journal
(1) Agents that can improve the uptake of drugs through the nasal mucosa, which may be used in conjunction with Nasya to increase efficacy.[6] (2) Substances used to improve the absorption of larger drug molecules when administered through the nasal route.[7]